25B-NBOMe<\/strong><\/a> is a potent synthetic phenethylamine derivative<\/strong> belonging to the NBOMe (N-benzyl-oxy-methyl) series<\/strong>, which also includes compounds such as 25I-NBOMe and 25C-NBOMe. These compounds are recognized for their high receptor selectivity<\/strong> and unique pharmacological profiles<\/strong><\/a>, making them valuable for neuroscientific and receptor-binding studies<\/strong>.<\/p>\n Developed in the early 2000s during academic research into 2C-series phenethylamines, 25B-NBOMe<\/strong> acts primarily as a 5-HT2A receptor agonist<\/strong>, a receptor subtype in the serotonin family that plays a critical role in cognition, perception, and mood regulation. This makes it a compound of significant interest for receptor mapping and behavioral pharmacology<\/strong> research.<\/p>\n Chemical Name:<\/strong> 2-(4-Bromo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine NBOMe (N-benzyl-oxy-methyl) <\/strong> is structurally derived from 2C-B (4-bromo-2,5-dimethoxyphenethylamine)<\/strong> by adding an N-(2-methoxybenzyl)<\/strong> group to the amine. This modification significantly increases its binding affinity<\/strong> for serotonin receptors, especially the 5-HT2A receptor<\/strong>, often resulting in sub-nanomolar potency<\/strong>.<\/p>\n Key physicochemical properties include:<\/strong><\/p>\n Appearance: Off-white crystalline powder<\/p>\n<\/li>\n Solubility: Soluble in ethanol, dimethyl sulfoxide (DMSO), and other organic solvents<\/p>\n<\/li>\n Stability: Stable under dry, cool, and light-protected storage conditions<\/p>\n<\/li>\n Storage Recommendations: Store at 2\u20138\u00b0C, tightly sealed, and away from direct sunlight<\/p>\n<\/li>\n<\/ul>\n These properties make 25B-NBOMe ideal for analytical research<\/strong>, such as liquid chromatography (LC)<\/strong>, mass spectrometry (MS)<\/strong>, and receptor binding assays<\/strong>.<\/p>\n NBOMe (N-benzyl-oxy-methyl) has gained considerable interest among pharmacologists, neuroscientists, and analytical chemists<\/strong> for its high potency and selectivity<\/strong> at serotonin receptor subtypes. Some of its common research applications<\/strong> include:<\/p>\n 25B-NBOMe is frequently utilized to explore the 5-HT2A receptor binding mechanisms<\/strong>. Due to its high affinity, it allows researchers to study how serotonin agonists interact with neural receptors involved in sensory processing, cognition, and mood.<\/p>\n By comparing 25B-NBOMe with analogs like 25I-NBOMe and 25C-NBOMe, scientists can analyze structure\u2013activity relationships<\/strong> within the NBOMe family. This data helps understand how halogen substitution affects potency, efficacy, and receptor selectivity.<\/p>\n 25B-NBOMe also provides a model for studying drug metabolism<\/strong> in vitro. Analytical studies often focus on how the compound is metabolized by cytochrome P450 enzymes<\/strong>, generating valuable insights for toxicology and biochemical research.<\/p>\n Because of its well-defined chemical structure, 25B-NBOMe serves as a reference standard<\/strong> for chromatographic calibration<\/strong>, mass spectral analysis<\/strong>, and forensic toxicology<\/strong> applications. Researchers use it to identify and compare similar compounds in biological or environmental samples.<\/p>\n Important Notice:<\/strong> Safety Guidelines:<\/strong><\/p>\n Avoid inhalation, ingestion, or skin contact.<\/p>\n<\/li>\n Always use gloves, protective eyewear, and lab coats.<\/p>\n<\/li>\n Store securely, away from unauthorized access.<\/p>\n<\/li>\n<\/ul>\n Legal Status:<\/strong> When sourcing 25B-NBOMe, purity and authenticity<\/strong> are crucial for reproducible research results. High-quality 25B-NBOMe ensures:<\/p>\n Consistent analytical outcomes<\/strong> in chromatography and spectroscopy.<\/p>\n<\/li>\n Reliable receptor binding data<\/strong> due to accurate molecular integrity.<\/p>\n<\/li>\n Reduced risk of contamination<\/strong> or unwanted byproducts.<\/p>\n<\/li>\n<\/ul>\n Our 25B-NBOMe is laboratory-tested and HPLC-verified<\/strong>, offering researchers the assurance of superior chemical quality and verified composition<\/strong>. Each batch includes detailed certificate of analysis (COA)<\/strong> and safety data sheet (SDS)<\/strong> to support compliance and traceability.<\/p>\n To maintain maximum stability and shelf life:<\/p>\n Keep the product in a tightly sealed container.<\/p>\n<\/li>\n Store at 2\u20138\u00b0C<\/strong> in a dry environment.<\/p>\n<\/li>\n Avoid exposure to direct sunlight and humidity.<\/p>\n<\/li>\n Handle only under low-light laboratory conditions.<\/p>\n<\/li>\n<\/ul>\n When stored correctly, 25B-NBOMe retains its structural integrity for extended periods, ensuring consistent performance across analytical applications.<\/p>\n 25B-NBOMe is a potent, high-affinity serotonin receptor agonist<\/strong> that has become an essential compound in receptor binding and neurochemical research<\/strong>. With its precise structure, high purity, and reproducible effects, it continues to play a key role in expanding our understanding of serotonin signaling<\/strong>, psychopharmacology<\/strong>, and structure\u2013activity relationships<\/strong> within the phenethylamine class.<\/p>\n Whether used for analytical calibration<\/strong>, neuroscience experiments<\/strong>, or toxicological research<\/strong>, 25B-NBOMe remains one of the most valuable NBOMe compounds available to the scientific community \u2014 provided it is handled responsibly and within legal and ethical guidelines.<\/p>\n Disclaimer:<\/strong> 25B-NBOMe is a highly potent synthetic compound from the NBOMe series<\/strong>, primarily used in neuroscientific and pharmacological research<\/strong>. Known for its strong serotonin receptor (5-HT2A) agonist activity<\/strong>, this chemical is valuable for studying receptor binding and psychoactive compound interactions.<\/p>\n With its high affinity and sensitivity<\/strong>, 25B-NBOMe enables precise experimental analysis at microgram levels. Researchers often explore its structure\u2013activity relationship (SAR)<\/strong> to understand how small molecular changes influence receptor behavior.<\/p>\n Key Details:<\/strong><\/p>\n Chemical Name:<\/strong> 2-(4-Bromo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine<\/p>\n<\/li>\n Molecular Formula:<\/strong> C18H22BrNO3<\/p>\n<\/li>\n Form:<\/strong> Fine powder (for research use only)<\/p>\n<\/li>\n Purity:<\/strong> \u226598% analytical grade<\/p>\n<\/li>\n<\/ul>\n","protected":false},"featured_media":5382,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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Common Name:<\/strong> 25B-NBOMe
Molecular Formula:<\/strong> C18H22BrNO3
Molecular Weight:<\/strong> 380.28 g\/mol
Form:<\/strong> Powder or crystalline solid
Purity:<\/strong> \u2265 98% (HPLC verified)
Intended Use:<\/strong> Laboratory and analytical research only<\/p>\n
\nChemical and Structural Characteristics<\/h3>\n
\n
\nApplications and Research Significance<\/h3>\n
1. Receptor Binding Studies<\/strong><\/h4>\n
2. Structure-Activity Relationship (SAR) Analysis<\/strong><\/h4>\n
3. Pharmacokinetic and Metabolic Profiling<\/strong><\/h4>\n
4. Spectroscopic and Analytical Reference<\/strong><\/h4>\n
\nSafety, Handling, and Legal Notice<\/h3>\n
25B-NBOMe is a research chemical<\/strong> and not approved for human consumption<\/strong>. It is not intended for veterinary or therapeutic use<\/strong>. All handling should be performed by qualified personnel in a controlled laboratory setting<\/strong> equipped with appropriate protective equipment.<\/p>\n\n
The legality of 25B-NBOMe varies by jurisdiction. In some countries, it is classified as a controlled substance<\/strong> due to its psychoactive potential. Researchers are responsible for ensuring compliance with local, state, and federal regulations<\/strong> before purchase or use.<\/p>\n
\nWhy Choose High-Quality 25B-NBOMe for Research?<\/h3>\n
\n
\nStorage and Stability Recommendations<\/h3>\n
\n
\nSummary<\/h3>\n
\n
This product is sold strictly for research and analytical purposes only<\/strong>. It is not for human or animal consumption<\/strong>. Always comply with your local laws and regulations before purchase or use.<\/p>\n","protected":false},"excerpt":{"rendered":"\n