{"id":5404,"date":"2026-10-18T02:10:37","date_gmt":"2026-10-18T02:10:37","guid":{"rendered":"https:\/\/legitchem.com\/?post_type=product&p=5404"},"modified":"2026-10-20T11:37:25","modified_gmt":"2026-10-20T11:37:25","slug":"2f-dck-2-fluorodeschloroketamine","status":"publish","type":"product","link":"https:\/\/legitchem.com\/fr\/2f-dck-2-fluorodeschloroketamine\/","title":{"rendered":"2F-DCK (2-Fluorodeschloroketamine)"},"content":{"rendered":"

2F-DCK (2-Fluorodeschloroketamine): Comprehensive Product Overview<\/strong><\/h2>\n

Introduction to 2F-DCK (2-Fluorodeschloroketamine)<\/strong><\/h3>\n

2F-DCK (2-Fluorodeschloroketamine)<\/strong><\/a> is a dissociative arylcyclohexylamine<\/strong> belonging to the same chemical family as ketamine and deschloroketamine (DCK)<\/strong>. It has gained notable attention in the scientific community for its unique pharmacological profile<\/strong> and structural similarity to ketamine<\/strong>, making it an important subject of research in neuropharmacology, receptor binding studies, and behavioral neuroscience<\/strong>.<\/p>\n

Researchers often study 2F-DCK(2-Fluorodeschloroketamine) for its NMDA receptor antagonist activity<\/strong><\/a>, which is believed to contribute to its dissociative effects and potential therapeutic mechanisms. Its chemical structure, which includes a fluorine atom substitution<\/strong>, alters its lipophilicity and metabolism, providing a valuable comparison model for understanding how halogen substitution influences arylcyclohexylamine pharmacodynamics.<\/p>\n

Chemical Name:<\/strong> 2-Fluorodeschloroketamine
Common Names:<\/strong> 2F-DCK, Fluoroketamine, 2-Fl-2\u2019-Oxo-PCM
Chemical Formula:<\/strong> C13H16FNO
Molecular Weight:<\/strong> 221.27 g\/mol
IUPAC Name:<\/strong> (R,S)-2-(2-Fluorophenyl)-2-methylamino-cyclohexanone
Purity:<\/strong> \u2265 98% (analytical standard grade)
Form:<\/strong> Crystalline powder
Intended Use:<\/strong> Laboratory and forensic research purposes only<\/p>\n

Chemical and Structural Properties of 2F-DCK (2-Fluorodeschloroketamine)<\/strong><\/h3>\n

2F-DCK(2-Fluorodeschloroketamine) is structurally related to ketamine (2-chloroketamine)<\/strong>, with the primary difference being the replacement of the chlorine atom in ketamine\u2019s phenyl ring with a fluorine atom. This seemingly minor alteration results in significant changes in receptor binding affinity, potency, and metabolic stability<\/strong>.<\/p>\n

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  • \n

    CAS Number:<\/strong> Not assigned (research chemical)<\/p>\n<\/li>\n

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    Class:<\/strong> Arylcyclohexylamine dissociative<\/p>\n<\/li>\n

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    Appearance:<\/strong> Off-white to light crystalline powder<\/p>\n<\/li>\n

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    Solubility:<\/strong> Soluble in ethanol, methanol, and dimethyl sulfoxide (DMSO); slightly soluble in water<\/p>\n<\/li>\n

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    Storage Conditions:<\/strong> Store in a cool, dry place, protected from light and moisture. Recommended temperature: below 25\u00b0C<\/p>\n<\/li>\n<\/ul>\n

    This compound\u2019s high analytical purity ensures that it is suitable for precise qualitative and quantitative analysis<\/strong> in controlled laboratory environments.<\/p>\n

    Pharmacological Background of 2F-DCK (2-Fluorodeschloroketamine)<\/strong><\/h3>\n

    While 2F-DCK(2-Fluorodeschloroketamine) is not approved for human or veterinary use<\/strong>, it remains an important research analog<\/strong> for understanding the mechanism of action of NMDA receptor antagonists. Studies suggest that 2F-DCK interacts primarily with:<\/p>\n

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      N-methyl-D-aspartate (NMDA) receptors<\/strong> \u2013 acting as a non-competitive antagonist<\/p>\n<\/li>\n

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      Sigma receptors<\/strong> \u2013 potentially contributing to psychoactive and neuroprotective effects<\/p>\n<\/li>\n

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      Dopaminergic and serotonergic systems<\/strong> \u2013 though to a lesser degree, offering insight into its broader neurochemical interactions<\/p>\n<\/li>\n<\/ul>\n

      Researchers investigating 2F-DCK(2-Fluorodeschloroketamine) often focus on its comparative efficacy, receptor affinity, and metabolism<\/strong> relative to ketamine and DCK. Its longer half-life and altered potency provide valuable data for pharmacokinetic modeling and structure-activity relationship (SAR) studies.<\/p>\n

      Applications in Research 2F-DCK (2-Fluorodeschloroketamine)<\/strong><\/h3>\n

      2F-DCK<\/strong> is utilized across multiple research fields, including:<\/p>\n

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      1. \n

        Pharmacological Studies<\/strong>
        Used to explore NMDA receptor function, ion channel modulation, and neural plasticity.<\/p>\n<\/li>\n

      2. \n

        Behavioral and Cognitive Research<\/strong>
        2F-DCK(2-Fluorodeschloroketamine) serves as a model for dissociation, perception alteration, and neurocognitive modulation in controlled experiments.<\/p>\n<\/li>\n

      3. \n

        Analytical Chemistry and Forensic Testing<\/strong>
        Researchers employ 2F-DCK as a reference material<\/strong> for mass spectrometry, chromatography, and toxicological profiling.<\/p>\n<\/li>\n

      4. \n

        Structure-Activity Relationship (SAR) Studies<\/strong>
        The fluorine substitution provides valuable data for developing next-generation NMDA receptor antagonists with optimized efficacy and safety.<\/p>\n<\/li>\n<\/ol>\n

        Safety and Handling Information 2F-DCK (2-Fluorodeschloroketamine)<\/strong><\/h3>\n

        2F-DCK(2-Fluorodeschloroketamine) should only be handled by trained professionals in equipped laboratories<\/strong>. Proper safety procedures, including the use of gloves, protective eyewear, and laboratory coats, are essential.
        This compound is not for human consumption, medical treatment, or recreational use<\/strong>. Ingestion or misuse may result in serious health risks.<\/p>\n

        Safety Recommendations:<\/strong><\/p>\n

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        • \n

          Avoid inhalation or contact with skin and eyes.<\/p>\n<\/li>\n

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          Store securely, away from heat and direct sunlight.<\/p>\n<\/li>\n

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          Dispose of unused material following local chemical safety regulations.<\/p>\n<\/li>\n<\/ul>\n

          Legal and Regulatory Status<\/strong><\/h3>\n

          The legal classification of 2F-DCK(2-Fluorodeschloroketamine) varies by country and jurisdiction. In many regions, it remains an uncontrolled research chemical<\/strong>, while others have implemented specific analog acts or psychoactive substance regulations<\/strong> that may apply to compounds structurally similar to ketamine.<\/p>\n

          Researchers are strongly advised to verify local and international regulations<\/strong> before purchase, import, or use of 2F-DCK in any project.<\/p>\n

          Why Choose High-Quality 2F-DCK (2-Fluorodeschloroketamine) for Research<\/strong><\/h3>\n

          When conducting scientific research, compound purity and authenticity<\/strong> are critical. High-quality 2F-DCK ensures:<\/p>\n

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            Reliable and reproducible analytical results<\/strong><\/p>\n<\/li>\n

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            Accurate pharmacological modeling<\/strong><\/p>\n<\/li>\n

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            Enhanced safety in controlled experiments<\/strong><\/p>\n<\/li>\n

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            Confidence in structural and receptor-based studies<\/strong><\/p>\n<\/li>\n<\/ul>\n

            Reputable suppliers provide batch-specific Certificates of Analysis (COA)<\/strong> and Material Safety Data Sheets (MSDS)<\/strong> for full transparency.<\/p>\n

            Conclusion<\/strong><\/h3>\n

            2F-DCK (2-Fluorodeschloroketamine)<\/strong> represents a valuable addition to the expanding library of arylcyclohexylamine research compounds<\/strong>. Its unique fluorine substitution makes it a key analog for investigating NMDA receptor modulation, dissociative pharmacology, and structure-function relationships<\/strong> among ketamine derivatives.<\/p>\n

            For laboratory and forensic researchers<\/strong>, 2F-DCK(2-Fluorodeschloroketamine) offers a consistent, high-purity standard for analytical, pharmacological, and biochemical studies.<\/p>\n

            \n

            Note:<\/strong> 2F-DCK is sold strictly for laboratory research purposes only<\/strong>. It is not intended for human or veterinary use<\/strong>. Ensure compliance with all applicable laws and regulations before ordering or handling.<\/p>\n<\/blockquote>","protected":false},"excerpt":{"rendered":"

            2F-DCK(2-Fluorodeschloroketamine)<\/strong>, is a dissociative compound from the arylcyclohexylamine class, closely related to ketamine and DCK. Known for its high purity and reliable performance<\/strong>, it has become a popular choice among professional researchers<\/strong> exploring NMDA receptor antagonists and dissociative mechanisms.<\/p>\n

            This compound offers unique pharmacological properties<\/strong>, including potential anesthetic and psychotropic research applications. 2F-DCK is typically used in neuroscientific and analytical studies<\/strong> focused on receptor binding, neural dissociation, and molecular behavior.<\/p>","protected":false},"featured_media":5422,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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