{"id":5429,"date":"2026-10-18T02:10:43","date_gmt":"2026-10-18T02:10:43","guid":{"rendered":"https:\/\/legitchem.com\/?post_type=product&#038;p=5429"},"modified":"2026-10-20T11:37:25","modified_gmt":"2026-10-20T11:37:25","slug":"methoxphenidine-mxpcp","status":"publish","type":"product","link":"https:\/\/legitchem.com\/ru\/methoxphenidine-mxpcp\/","title":{"rendered":"Methoxphenidine (MXPCP)"},"content":{"rendered":"<h2 data-start=\"241\" data-end=\"326\"><strong data-start=\"244\" data-end=\"326\">Methoxphenidine (MXPCP) \u2013 Research Chemical for Analytical and Educational Use<\/strong><\/h2>\n<h3 data-start=\"328\" data-end=\"344\"><strong data-start=\"332\" data-end=\"344\">Overview<\/strong><\/h3>\n<p data-start=\"346\" data-end=\"970\">Methoxphenidine ( MXPCP), commonly referred to as <strong data-start=\"387\" data-end=\"396\">MXPCP<\/strong>, is a dissociative compound belonging to the <a href=\"https:\/\/researchchemsupplier.com\/product-category\/dissociatives\/\" target=\"_blank\" rel=\"noopener\"><strong data-start=\"442\" data-end=\"465\">arylcyclohexylamine<\/strong><\/a> class, structurally related to substances such as <strong data-start=\"516\" data-end=\"539\">phencyclidine (PCP)<\/strong> and <strong data-start=\"544\" data-end=\"556\">ketamine<\/strong>. Originally synthesized in the early 2010s, MXPCP has since attracted significant attention within research communities for its <strong data-start=\"685\" data-end=\"719\">unique pharmacological profile<\/strong> and its ability to act as an <strong data-start=\"749\" data-end=\"777\">NMDA receptor antagonist<\/strong>. This makes it a valuable compound for <strong data-start=\"817\" data-end=\"887\">neurochemical, psychopharmacological, and receptor-binding studies<\/strong> aimed at understanding the mechanisms of perception, cognition, and consciousness.<\/p>\n<h3 data-start=\"972\" data-end=\"1000\"><strong data-start=\"976\" data-end=\"1000\">Chemical Information of Methoxphenidine (MXPCP)<\/strong><\/h3>\n<ul data-start=\"1002\" data-end=\"1352\">\n<li data-start=\"1002\" data-end=\"1065\">\n<p data-start=\"1004\" data-end=\"1065\"><strong data-start=\"1004\" data-end=\"1019\">IUPAC Name:<\/strong> 1-[1-(2-methoxyphenyl)cyclohexyl]piperidine<\/p>\n<\/li>\n<li data-start=\"1066\" data-end=\"1100\">\n<p data-start=\"1068\" data-end=\"1100\"><strong data-start=\"1068\" data-end=\"1089\">Chemical Formula:<\/strong> C18H27NO<\/p>\n<\/li>\n<li data-start=\"1101\" data-end=\"1139\">\n<p data-start=\"1103\" data-end=\"1139\"><strong data-start=\"1103\" data-end=\"1124\">Molecular Weight:<\/strong> 273.41 g\/mol<\/p>\n<\/li>\n<li data-start=\"1140\" data-end=\"1194\">\n<p data-start=\"1142\" data-end=\"1194\"><strong data-start=\"1142\" data-end=\"1155\">Synonyms:<\/strong> MXP, Methoxyphencyclidine, 2-MeO-PCP<\/p>\n<\/li>\n<li data-start=\"1195\" data-end=\"1238\">\n<p data-start=\"1197\" data-end=\"1238\"><strong data-start=\"1197\" data-end=\"1216\">Chemical Class:<\/strong> Arylcyclohexylamine<\/p>\n<\/li>\n<li data-start=\"1239\" data-end=\"1314\">\n<p data-start=\"1241\" data-end=\"1314\"><strong data-start=\"1241\" data-end=\"1250\">Form:<\/strong> Fine crystalline or powder (varies by supplier specification)<\/p>\n<\/li>\n<li data-start=\"1315\" data-end=\"1352\">\n<p data-start=\"1317\" data-end=\"1352\"><strong data-start=\"1317\" data-end=\"1328\">Purity:<\/strong> \u226598% (research grade)<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1354\" data-end=\"1601\">MXPCP is characterized by its <a href=\"https:\/\/getmetabolite.com\/product\/mxp\" target=\"_blank\" rel=\"noopener\"><strong data-start=\"1384\" data-end=\"1411\">high chemical stability<\/strong><\/a> and <strong data-start=\"1416\" data-end=\"1443\">strong binding affinity<\/strong> to the NMDA receptor site, which makes it an ideal candidate for <strong data-start=\"1509\" data-end=\"1559\">binding assays, analytical reference standards<\/strong>, and <strong data-start=\"1565\" data-end=\"1600\">forensic toxicology calibration<\/strong>.<\/p>\n<h3 data-start=\"1603\" data-end=\"1658\"><strong data-start=\"1607\" data-end=\"1658\">Pharmacological Profile and Mechanism of Action<\/strong><\/h3>\n<p data-start=\"1660\" data-end=\"2065\">Methoxphenidine acts primarily as a <strong data-start=\"1696\" data-end=\"1740\">non-competitive NMDA receptor antagonist<\/strong>\u2014a mechanism shared by many dissociative anesthetics. By inhibiting the action of glutamate at NMDA receptors, MXPCP modulates excitatory neurotransmission within the central nervous system. Research suggests that this process is integral to understanding <strong data-start=\"1996\" data-end=\"2064\">neural plasticity, memory function, and consciousness modulation<\/strong>.<\/p>\n<p data-start=\"2067\" data-end=\"2469\">Additionally, some preliminary receptor mapping studies indicate potential <strong data-start=\"2142\" data-end=\"2209\">secondary interactions with dopamine and serotonin transporters<\/strong>, although these effects are far weaker compared to NMDA antagonism. This receptor selectivity contributes to MXPCP\u2019s unique <strong data-start=\"2334\" data-end=\"2376\">pharmacodynamic and behavioral profile<\/strong>, making it a subject of interest in modern <strong data-start=\"2420\" data-end=\"2468\">neuroscience and psychopharmacology research<\/strong>.<\/p>\n<h3 data-start=\"2471\" data-end=\"2503\"><strong data-start=\"2475\" data-end=\"2503\">Applications in Research<\/strong><\/h3>\n<p data-start=\"2505\" data-end=\"2659\">Methoxphenidine (MXPCP) is intended <strong data-start=\"2523\" data-end=\"2567\">strictly for scientific and forensic use<\/strong>. It should not be used for human or animal consumption. Its principal applications include:<\/p>\n<ol data-start=\"2661\" data-end=\"3494\">\n<li data-start=\"2661\" data-end=\"2848\">\n<p data-start=\"2664\" data-end=\"2848\"><strong data-start=\"2664\" data-end=\"2692\">Receptor Binding Studies<\/strong> \u2013 Examining the interaction between MXPCP and NMDA receptor subtypes to understand the structure\u2013activity relationship (SAR) of dissociative anesthetics.<\/p>\n<\/li>\n<li data-start=\"2849\" data-end=\"3027\">\n<p data-start=\"2852\" data-end=\"3027\"><strong data-start=\"2852\" data-end=\"2885\">Analytical Reference Standard<\/strong> \u2013 Utilized by analytical laboratories to <strong data-start=\"2927\" data-end=\"2969\">develop and validate detection methods<\/strong> such as <strong data-start=\"2978\" data-end=\"2997\">GC-MS, LC-MS\/MS<\/strong>, and <strong data-start=\"3003\" data-end=\"3024\">FTIR spectroscopy<\/strong>.<\/p>\n<\/li>\n<li data-start=\"3028\" data-end=\"3191\">\n<p data-start=\"3031\" data-end=\"3191\"><strong data-start=\"3031\" data-end=\"3057\">Neurochemical Research<\/strong> \u2013 Investigating glutamatergic signaling pathways, neuroplasticity, and the molecular underpinnings of consciousness and perception.<\/p>\n<\/li>\n<li data-start=\"3192\" data-end=\"3331\">\n<p data-start=\"3195\" data-end=\"3331\"><strong data-start=\"3195\" data-end=\"3224\">Toxicological Calibration<\/strong> \u2013 Used in forensic toxicology for identifying and quantifying novel dissociatives in biological samples.<\/p>\n<\/li>\n<li data-start=\"3332\" data-end=\"3494\">\n<p data-start=\"3335\" data-end=\"3494\"><strong data-start=\"3335\" data-end=\"3354\">Educational Use<\/strong> \u2013 Serving as a reference compound in academic settings for <strong data-start=\"3414\" data-end=\"3459\">chemical synthesis, structure elucidation<\/strong>, and <strong data-start=\"3465\" data-end=\"3493\">pharmacological modeling<\/strong>.<\/p>\n<\/li>\n<\/ol>\n<h3 data-start=\"3496\" data-end=\"3536\"><strong data-start=\"3500\" data-end=\"3536\">Physical and Chemical Properties of Methoxphenidine (MXPCP)<\/strong><\/h3>\n<ul data-start=\"3538\" data-end=\"3972\">\n<li data-start=\"3538\" data-end=\"3595\">\n<p data-start=\"3540\" data-end=\"3595\"><strong data-start=\"3540\" data-end=\"3555\">Appearance:<\/strong> White to off-white crystalline powder<\/p>\n<\/li>\n<li data-start=\"3596\" data-end=\"3699\">\n<p data-start=\"3598\" data-end=\"3699\"><strong data-start=\"3598\" data-end=\"3613\">Solubility:<\/strong> Soluble in ethanol, acetone, and other organic solvents; sparingly soluble in water<\/p>\n<\/li>\n<li data-start=\"3700\" data-end=\"3749\">\n<p data-start=\"3702\" data-end=\"3749\"><strong data-start=\"3702\" data-end=\"3720\">Boiling Point:<\/strong> Approx. 390\u00b0C (decomposes)<\/p>\n<\/li>\n<li data-start=\"3750\" data-end=\"3972\">\n<p data-start=\"3752\" data-end=\"3972\"><strong data-start=\"3752\" data-end=\"3775\">Storage Conditions:<\/strong> Store in a cool, dry, and well-ventilated area, away from direct sunlight and moisture. For optimal preservation, it should be kept in airtight containers under controlled laboratory conditions.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"3974\" data-end=\"4148\">Proper handling procedures and <strong data-start=\"4005\" data-end=\"4044\">personal protective equipment (PPE)<\/strong> such as gloves, goggles, and lab coats are mandatory when working with MXPCP in a research environment.<\/p>\n<h3 data-start=\"4150\" data-end=\"4192\"><strong data-start=\"4154\" data-end=\"4192\">Safety, Handling, and Legal Status<\/strong><\/h3>\n<p data-start=\"4194\" data-end=\"4527\"><strong data-start=\"4194\" data-end=\"4206\">Warning:<\/strong> Methoxphenidine (MXPCP) is a <strong data-start=\"4236\" data-end=\"4257\">research chemical<\/strong> and <strong data-start=\"4262\" data-end=\"4306\">not approved for human or veterinary use<\/strong>. It may pose <strong data-start=\"4320\" data-end=\"4347\">health risks if misused<\/strong>, including potential neurotoxicity and dissociative effects similar to other NMDA antagonists. Researchers are advised to handle it following standard laboratory safety protocols.<\/p>\n<p data-start=\"4529\" data-end=\"4855\">The <strong data-start=\"4533\" data-end=\"4558\">legal status of MXPCP<\/strong> varies by country. In some jurisdictions, it may be <strong data-start=\"4611\" data-end=\"4651\">classified as a controlled substance<\/strong> or an <strong data-start=\"4658\" data-end=\"4675\">analog of PCP<\/strong>, subject to restrictions under analogue laws. Users must ensure compliance with <strong data-start=\"4756\" data-end=\"4797\">local, state, and federal regulations<\/strong> before purchasing, possessing, or studying this compound.<\/p>\n<h3 data-start=\"4857\" data-end=\"4886\"><strong data-start=\"4861\" data-end=\"4886\">Storage and Stability<\/strong><\/h3>\n<p data-start=\"4888\" data-end=\"4936\">For long-term stability, Methoxphenidine (MXPCP) should be stored:<\/p>\n<ul data-start=\"4937\" data-end=\"5091\">\n<li data-start=\"4937\" data-end=\"4980\">\n<p data-start=\"4939\" data-end=\"4980\">At temperatures between <strong data-start=\"4963\" data-end=\"4978\">2\u00b0C and 8\u00b0C<\/strong><\/p>\n<\/li>\n<li data-start=\"4981\" data-end=\"5030\">\n<p data-start=\"4983\" data-end=\"5030\">In an <strong data-start=\"4989\" data-end=\"5028\">airtight, light-resistant container<\/strong><\/p>\n<\/li>\n<li data-start=\"5031\" data-end=\"5091\">\n<p data-start=\"5033\" data-end=\"5091\">In a <strong data-start=\"5038\" data-end=\"5066\">low-humidity environment<\/strong> to prevent degradation<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"5093\" data-end=\"5242\">Under these conditions, the compound maintains its chemical integrity for an extended period, making it suitable for longitudinal analytical studies.<\/p>\n<h3 data-start=\"5244\" data-end=\"5269\"><strong data-start=\"5248\" data-end=\"5269\">Quality Assurance<\/strong><\/h3>\n<p data-start=\"5271\" data-end=\"5620\">Each batch of Methoxphenidine (MXPCP) undergoes <strong data-start=\"5319\" data-end=\"5355\">rigorous analytical verification<\/strong> using advanced chromatographic and spectrometric techniques, ensuring a <strong data-start=\"5428\" data-end=\"5453\">minimum purity of 98%<\/strong>. Certificates of Analysis (COA) and Material Safety Data Sheets (MSDS) are provided upon request to verify quality and assist in compliance with laboratory standards.<\/p>\n<h3 data-start=\"5622\" data-end=\"5640\"><strong data-start=\"5626\" data-end=\"5640\">Conclusion<\/strong><\/h3>\n<p data-start=\"5642\" data-end=\"5971\">Methoxphenidine (MXPCP) remains an essential compound for researchers exploring the <strong data-start=\"5726\" data-end=\"5774\">complex dynamics of NMDA receptor modulation<\/strong> and <strong data-start=\"5779\" data-end=\"5808\">dissociative pharmacology<\/strong>. Its <strong data-start=\"5814\" data-end=\"5879\">distinct chemical structure, stability, and receptor affinity<\/strong> make it a valuable reference material for forensic, neurochemical, and analytical research.<\/p>\n<p data-start=\"5973\" data-end=\"6196\">When handled responsibly and used within the parameters of laboratory research, MXPCP contributes meaningfully to scientific understanding of <strong data-start=\"6115\" data-end=\"6193\">neurotransmission, anesthetic development, and receptor-binding mechanisms<\/strong>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p data-start=\"70\" data-end=\"488\">Methoxphenidine (MXPCP) is a <strong data-start=\"97\" data-end=\"135\">novel arylcyclohexylamine compound<\/strong> known for its <strong data-start=\"150\" data-end=\"206\">dissociative and NMDA receptor antagonist properties<\/strong>, making it a valuable substance for <strong data-start=\"243\" data-end=\"306\">advanced chemical research and neuropharmacological studies<\/strong>. Structurally related to compounds like PCP and MXE, MXPCP offers researchers a <strong data-start=\"387\" data-end=\"485\">unique profile for exploring receptor binding, cognitive modulation, and anesthetic mechanisms<\/strong>.<\/p>\n<p data-start=\"490\" data-end=\"749\">This high-purity research chemical is supplied for <strong data-start=\"541\" data-end=\"579\">laboratory and analytical use only<\/strong>. Researchers value MXPCP for its <strong data-start=\"613\" data-end=\"667\">long duration, potent dissociative characteristics<\/strong>, and potential to <strong data-start=\"686\" data-end=\"746\">enhance understanding of glutamatergic neurotransmission<\/strong>.<\/p>","protected":false},"featured_media":5454,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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