HXE (Hydroxetamine) is a hydroxylated ketamine-class analog within the arylcyclohexylamine family. Structurally related to ketamine and other substituted cyclohexylamines, HXE features a hydroxy (-OH) substitution, making it relevant for structure–activity relationship (SAR) research, analytical profiling, and comparative chemical studies.
Within the EU and the Netherlands, HXE is supplied strictly as a laboratory reference material and has no approved medical, therapeutic, or commercial applications.
Research & Chemical Summary
| Attribute | Details |
|---|---|
| Common Name | HXE |
| Chemical Name | Hydroxetamine |
| Chemical Class | Arylcyclohexylamine |
| Research Status | Research Chemical 🧪 |
| Physical Form | Powder |
| Intended Use | Laboratory & analytical research only |
| Region Focus | Europe / Netherlands (EU) |
Scientific & Analytical Context
HXE is typically referenced in research environments for:
-
Comparative analysis with ketamine and related analogs
-
Structure–activity relationship (SAR) studies
-
Analytical method development (GC/MS, LC/MS, HPLC)
-
Reference material for chemical identification
Publicly available information focuses mainly on chemical structure and analytical characteristics, with limited formal pharmacological or toxicological data in the research-chemical context.
Chemical Specifications
| Property | Value |
|---|---|
| Molecular Formula | C₁₃H₁₉NO₂ |
| Molecular Weight | ~221.29 g/mol |
| CAS Number | 1400742-13-6 (research reference) |
| IUPAC Name | 2-(methylamino)-2-(3-hydroxyphenyl)cyclohexan-1-one |
| PubChem CID | 162199961 |
Structural Identifiers
| Identifier | Data |
|---|---|
| SMILES | CNC1(CCCCC1=O)c2cccc(O)c2 |
| InChIKey | QJZJXQKJQZJXQK-UHFFFAOYSA-N |
Key Research Characteristics
| Feature | Summary |
|---|---|
| Compound Type | Ketamine-class analog |
| Structural Interest | Hydroxylated arylcyclohexylamine |
| Research Focus | SAR, analytical & forensic studies |
| Documentation | CAS, molecular & structural data |
Compliance & Handling Notice
This product is supplied exclusively for laboratory and analytical research purposes.
Not intended for human or animal use.





